Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc31a1tm1Djt
Name:	solute carrier family 31, member 1; targeted mutation 1, Dennis J Thiele
MGI ID:	MGI:2388121
Synonyms:	Ctr1-/-
Gene:	Slc31a1  Location: Chr4:62278964-62310006 bp, + strand  Genetic Position: Chr4, 33.11 cM, cytoband C1-C2
Alliance:	Slc31a1tm1Djt page

Germline Transmission:	Earliest citation of germline transmission: J:69897
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the gene was deleted and replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were observed at day E10.5, but not did not survive past day E12.5. (J:69897)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc31a1 Mutation:	40 strains or lines available

Original:	J:69897 Lee J, et al., Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6842-7
All:	4 reference(s)