Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mxd1tm1Rne
Name:	MAX dimerization protein 1; targeted mutation 1, Robert N Eisenman
MGI ID:	MGI:2387993
Synonyms:	Mad1tm1
Gene:	Mxd1  Location: Chr6:86624026-86646099 bp, - strand  Genetic Position: Chr6, 37.75 cM
Alliance:	Mxd1tm1Rne page

Germline Transmission:	Earliest citation of germline transmission: J:45945
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequence encompassing the 5' untranslated region and exon 1 were replaced by a PGK-neo cassette inserted by homologous recombination. Transcript was undetected by RT-PCR analysis of a variety of tissues obtained from homozygous mutant mice. (J:45945)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mxd1 Mutation:	17 strains or lines available

Original:	J:45945 Foley KP, et al., Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. EMBO J. 1998 Feb 2;17(3):774-85
All:	3 reference(s)