Pou3f1tm2Mejr
Targeted Allele Detail
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Symbol: |
Pou3f1tm2Mejr |
Name: |
POU domain, class 3, transcription factor 1; targeted mutation 2, Dies Meijer |
MGI ID: |
MGI:2387951 |
Synonyms: |
Oct-6Puro |
Gene: |
Pou3f1 Location: Chr4:124551439-124554448 bp, + strand Genetic Position: Chr4, 57.86 cM
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Alliance: |
Pou3f1tm2Mejr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:78939
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A Schwann cell specific knockout was generated by replacing a 4.3 kb Schwann cell specific enhancer element downstream of the coding region with a floxed puromycin selection cassette. Mice carrying this allele were used to generate Pou3f1tm2.1Mejr.
(J:78939)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pou3f1 Mutation: |
14 strains or lines available
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Original: |
J:78939 Ghazvini M, et al., A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration. EMBO J. 2002 Sep 2;21(17):4612-20 |
All: |
1 reference(s) |
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