Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcl2l10tm1Pmc
Name:	Bcl2-like 10; targeted mutation 1, Peter J McKinnon
MGI ID:	MGI:2387943
Synonyms:	Diva-
Gene:	Bcl2l10  Location: Chr9:75255040-75258922 bp, + strand  Genetic Position: Chr9, 42.3 cM, cytoband D
Alliance:	Bcl2l10tm1Pmc page

Germline Transmission:	Earliest citation of germline transmission: J:78924
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 and 2 were replaced by a neomycin selection cassette inserted by homologous recombination. The deleted region encompassed the entire coding region of the endogenous locus, thus transcript was undetected by Northern blot analysis of ovarian RNA obtained from homozygous mutant mice. (J:78924)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl2l10 Mutation:	6 strains or lines available

Original:	J:78924 Russell HR, et al., Murine ovarian development is not affected by inactivation of the bcl-2 family member diva. Mol Cell Biol. 2002 Oct;22(19):6866-70
All:	1 reference(s)