Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	H2az1tm1Ily
Name:	H2A.Z variant histone 1; targeted mutation 1, Ian Lyons
MGI ID:	MGI:2387764
Synonyms:	H2A.Z-
Gene:	H2az1  Location: Chr3:137570248-137572683 bp, + strand  Genetic Position: Chr3, 63.94 cM
Alliance:	H2az1tm1Ily page

Germline Transmission:	Earliest citation of germline transmission: J:71146
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The promoter regions and exons 1 and 2 were replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were detected by PCR genotyping up to day E6.5. (J:71146)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any H2az1 Mutation:	13 strains or lines available

Original:	J:71146 Faast R, et al., Histone variant H2A.Z is required for early mammalian development. Curr Biol. 2001 Aug 7;11(15):1183-7
All:	1 reference(s)