Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hrh3tm1Twl
Name:	histamine receptor H3; targeted mutation 1, Timothy W Lovenberg
MGI ID:	MGI:2387415
Synonyms:	H3R-
Gene:	Hrh3  Location: Chr2:179741258-179746264 bp, - strand  Genetic Position: Chr2, 102.62 cM
Alliance:	Hrh3tm1Twl page

Germline Transmission:	Earliest citation of germline transmission: J:79168
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin selection cassette replaced a 0.7 kb fragment containing exon 1 and part of exon 2. (J:79168) Inheritance:    Not Specified

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hrh3 Mutation:	20 strains or lines available

Original:	J:79168 Toyota H, et al., Behavioral characterization of mice lacking histamine H(3) receptors. Mol Pharmacol. 2002 Aug;62(2):389-97
All:	18 reference(s)