Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cenpbtm1Gmay
Name:	centromere protein B; targeted mutation 1, Gregory S May
MGI ID:	MGI:2386968
Synonyms:	Cenp-B -
Gene:	Cenpb  Location: Chr2:131019209-131021974 bp, - strand  Genetic Position: Chr2, 63.29 cM
Alliance:	Cenpbtm1Gmay page

Germline Transmission:	Earliest citation of germline transmission: J:53053
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: 1.7 kb of the gene (from 65 bp upstream of the ATG start codon to 105 bp upstream of the stop codon) was deleted and replaced with a PGK-neo cassette. Absence of gene expression in homozygous mutants was confirmed by Western blot analysis of mouse embryonic fibroblasts (MEFs) derived from E10.5 embryos. (J:53053)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cenpb Mutation:	18 strains or lines available

Original:	J:53053 Kapoor M, et al., The cenpB gene is not essential in mice. Chromosoma. 1998 Dec;107(8):570-6
All:	1 reference(s)