Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	S100btm1Daoh
Name:	S100 protein, beta polypeptide, neural; targeted mutation 1, Alexander Marks
MGI ID:	MGI:2386179
Synonyms:	S100B-KO
Gene:	S100b  Location: Chr10:76089687-76096993 bp, + strand  Genetic Position: Chr10, 38.76 cM
Alliance:	S100btm1Daoh page

Germline Transmission:	Earliest citation of germline transmission: J:62728
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with a neomycin resistance gene via homologous recombination. Homozygous mutant animals did not express gene transcripts or protein products as determined by Northern and Western blot analysis of brain tissue. (J:62728)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any S100b Mutation:	14 strains or lines available

Original:	J:62728 Xiong Z, et al., Enhanced calcium transients in glial cells in neonatal cerebellar cultures derived from S100B null mice. Exp Cell Res. 2000 Jun 15;257(2):281-9
All:	17 reference(s)