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H1f3tm1Mkk
Targeted Allele Detail
Summary
Symbol: H1f3tm1Mkk
Name: H1.3 linker histone, cluster member; targeted mutation 1, Malathi K Kistler
MGI ID: MGI:2386170
Gene: H1f3  Location: Chr13:23739206-23739981 bp, + strand  Genetic Position: Chr13, 9.79 cM, cytoband A2-A3
Alliance: H1f3tm1Mkk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67063
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA construct, in which a 0.5 Kb fragment extending from upstream of the TATA box through codon 117 was replaced with a neomycin selection cassette, was inserted at the endogenous locus via homologous recombination. No immunoreactivity was observed in testes sections obtained from homozygous mutant mice. (J:67063)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any H1f3 Mutation:  8 strains or lines available
References
Original:  J:67063 Fantz D, et al., Mice with a targeted disruption of the h1t gene are fertile and undergo normal changes in structural chromosomal proteins during spermiogenesis. Biol Reprod. 2001 Feb;64(2):425-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory