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Nbl1tm1Rmh
Targeted Allele Detail
Summary
Symbol: Nbl1tm1Rmh
Name: NBL1, DAN family BMP antagonist; targeted mutation 1, Richard M Harland
MGI ID: MGI:2385843
Synonyms: Dandkol
Gene: Nbl1  Location: Chr4:138809595-138820304 bp, - strand  Genetic Position: Chr4, 70.57 cM, cytoband D3
Alliance: Nbl1tm1Rmh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67351
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The majority of exon 3 was replaced by a neo cassette containing a Beta-actin promoter. (J:67351)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nbl1 Mutation:  16 strains or lines available
References
Original:  J:67351 Dionne MS, et al., Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists. Mol Cell Biol. 2001 Jan;21(2):636-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory