Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol: Cited2tm1Ycy Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; targeted mutation 1, Yu-Chung Yang MGI ID: MGI:2385355 Synonyms: Cited2- Gene: Cited2  Location: Chr10:17598966-17601422 bp, + strand  Genetic Position: Chr10, 7.18 cM, cytoband A2 Alliance: Cited2tm1Ycy page

Eye phenotype and exencephaly of Cited2tm1Ycy/Cited2tm1Ycy mice Show the 3 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:78364
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the endogenous gene was replaced by a neomycin selection cassette. Transcript was undetected in by Northern blot analysis of total embryonic RNA. (J:78364)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	60 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cited2 Mutation:	23 strains or lines available

Original:	J:78364 Yin Z, et al., The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10488-93
All:	9 reference(s)