Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rad52tm1Aps
Name:	RAD52 homolog, DNA repair protein; targeted mutation 1, Albert Pastink
MGI ID:	MGI:2383953
Synonyms:	MmRAD52-
Gene:	Rad52  Location: Chr6:119879659-119899789 bp, + strand  Genetic Position: Chr6, 56.86 cM, cytoband G3
Alliance:	Rad52tm1Aps page

Germline Transmission:	Earliest citation of germline transmission: J:50357
Parent Cell Line:	IB10/E14IB10 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was replaced with a neomycin selection cassette. Western blot analysis of homozygous mutant ES cells showed an absence of both normal and truncated protein. (J:50357)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rad52 Mutation:	18 strains or lines available

Original:	J:50357 Rijkers T, et al., Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation. Mol Cell Biol. 1998 Nov;18(11):6423-9
All:	9 reference(s)