Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxb1tm1Blh
Name:	forkhead box B1; targeted mutation 1, Brigid L Hogan
MGI ID:	MGI:2183919
Synonyms:	mf3-, mf3tm1blh-
Gene:	Foxb1  Location: Chr9:69664992-69668222 bp, - strand  Genetic Position: Chr9, 38.76 cM
Alliance:	Foxb1tm1Blh page

Germline Transmission:	Earliest citation of germline transmission: J:40034
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region and 5' untranslated sequence were replace by a neomycin selection cassette. Transcript was undetected in the heads of homozygous mutant embryos via whole mount in situ hybridization. (J:40034)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxb1 Mutation:	16 strains or lines available

Original:	J:40034 Labosky PA, et al., The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. Development. 1997 APR;124(7):1263-1274
All:	1 reference(s)