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Diras1 Gene Detail
Summary
  • Symbol
    Diras1
  • Name
    DIRAS family, GTP-binding RAS-like 1
  • Synonyms
    Di-Ras1, GBTS1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183442
    NCBI Gene: 208666
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80855423-80861496 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183442
 protein coding gene Chr10:80855423-80862038 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017531
 protein coding gene Chr10:81695905-81701991 (-)
A/J MGP_AJ_G0017509
 protein coding gene Chr10:78814310-78820383 (-)
AKR/J MGP_AKRJ_G0017470
 protein coding gene Chr10:80977420-80983492 (-)
BALB/cJ MGP_BALBcJ_G0017471
 protein coding gene Chr10:79029288-79035358 (-)
C3H/HeJ MGP_C3HHeJ_G0017294
 protein coding gene Chr10:81059897-81065964 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017925
 protein coding gene Chr10:84495536-84501595 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015614
 protein coding gene Chr10:75019603-75025931 (-)
CAST/EiJ MGP_CASTEiJ_G0016861
 protein coding gene Chr10:81299731-81305756 (-)
CBA/J MGP_CBAJ_G0017266
 protein coding gene Chr10:87797644-87803731 (-)
DBA/2J MGP_DBA2J_G0017372
 protein coding gene Chr10:78009018-78015084 (-)
FVB/NJ MGP_FVBNJ_G0017366
 protein coding gene Chr10:77247044-77253119 (-)
LP/J MGP_LPJ_G0017443
 protein coding gene Chr10:82148340-82154183 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017392
 protein coding gene Chr10:89671938-89678018 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017966
 protein coding gene Chr10:80970352-80976446 (-)
PWK/PhJ MGP_PWKPhJ_G0016642
 protein coding gene Chr10:77906612-77912661 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016432
 protein coding gene Chr10:79920080-79926134 (-)
WSB/EiJ MGP_WSBEiJ_G0016921
 protein coding gene Chr10:81008740-81014804 (-)



Homology
more
  • Human Ortholog
    DIRAS1, DIRAS family GTPase 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIRAS1, DIRAS family GTPase 1
  • Synonyms
    Di-Ras1, GBTS1, RIG
  • Links
    NCBI Gene ID: 148252
    neXtProt AC: NX_O95057
    UniProt: O95057

  • Chr Location
    19p13.3; chr19:2714567-2721372 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    892
  • Tissues
    43
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043670 Ensembl Gene Model | MGI Sequence Detail 6074 C57BL/6J ±  kb
transcript ENSMUST00000055125 Ensembl | MGI Sequence Detail 2953 Not Applicable  
polypeptide ENSMUSP00000055605 Ensembl | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 5
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:344964 Reddy HM, et al., Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis. BMC Biol. 2021 Sep 9;19(1):198
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory