Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptentm1.1Mro
Name:	phosphatase and tensin homolog; targeted mutation 1.1, Silvia Marino
MGI ID:	MGI:2183285
Synonyms:	Ptendel
Gene:	Pten  Location: Chr19:32734977-32803560 bp, + strand  Genetic Position: Chr19, 28.14 cM
Alliance:	Ptentm1.1Mro page

Germline Transmission:	Earliest citation of germline transmission: J:77123
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector   Mutation details: This allele was generated by breeding mice carrying Ptentm1Mro with transgenic mice ubiquitously expressing cre recombinase. The expression of cre results in the excision of the floxed region containing exon 5. (J:77123)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pten Mutation:	81 strains or lines available

Original:	J:77123 Marino S, et al., PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development. 2002 Jul;129(14):3513-22
All:	2 reference(s)