Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pck1tm1Lre
Name:	phosphoenolpyruvate carboxykinase 1, cytosolic; targeted mutation 1, Lea Reshef
MGI ID:	MGI:2182390
Gene:	Pck1  Location: Chr2:172994866-173001067 bp, + strand  Genetic Position: Chr2, 95.79 cM, cytoband C1-qter
Alliance:	Pck1tm1Lre page

Germline Transmission:	Earliest citation of germline transmission: J:73977
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed PGK-neomycin resistance cassette replaced 50 bp of the adipose tissue-specific part of the promoter. (J:73977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pck1 Mutation:	47 strains or lines available

Original:	J:73977 Olswang Y, et al., A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):625-30
All:	1 reference(s)