Vdac3tm1Wjc
Targeted Allele Detail
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| Symbol: |
Vdac3tm1Wjc |
| Name: |
voltage-dependent anion channel 3; targeted mutation 1, Willam J Craigen |
| MGI ID: |
MGI:2182182 |
| Synonyms: |
VDAC3(-) |
| Gene: |
Vdac3 Location: Chr8:23067102-23083774 bp, - strand Genetic Position: Chr8, 11.42 cM
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| Alliance: |
Vdac3tm1Wjc page
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Structural abnormalities in sperm of Vdac3tm1Wjc/Vdac3tm1Wjc male mice
Show the 3 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:72188
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The last four exons were replaced with a neomycin selection cassette. Transcript was undetected in homozygous mutant mice via Northern blot analysis of various tissues. The absence of protein in homozygous mutant mice was demonstrated by Western blot analysis of various tissues and immunohistochemical staining of the testes.
(J:72188, J:78058)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Vdac3 Mutation: |
19 strains or lines available
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| Original: |
J:72188 Sampson MJ, et al., Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3. J Biol Chem. 2001 Oct 19;276(42):39206-12 |
| All: |
7 reference(s) |
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Analysis Tools
