Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Psmc3tm1Aki
Name:	proteasome (prosome, macropain) 26S subunit, ATPase 3; targeted mutation 1, Shizuo Akira
MGI ID:	MGI:2180548
Synonyms:	Psmc-
Gene:	Psmc3  Location: Chr2:90884361-90889783 bp, + strand  Genetic Position: Chr2, 50.44 cM
Alliance:	Psmc3tm1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:63395
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 0.3-kb region comprised of exon 7 and a portion of exon 8 and encoding a conserved ATPase domain was replaced with a neomycin selection cassette. The targeting event was confirmed by Southern blot analysis. (J:63395)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Psmc3 Mutation:	24 strains or lines available

Original:	J:63395 Sakao Y, et al., Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting. Genomics. 2000 Jul 1;67(1):1-7
All:	1 reference(s)