Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nhlh2tm1Irk
Name:	nescient helix loop helix 2; targeted mutation 1, Ilan R Kirsch
MGI ID:	MGI:2180391
Synonyms:	Nhlh2-
Gene:	Nhlh2  Location: Chr3:101917425-101922808 bp, + strand  Genetic Position: Chr3, 44.3 cM
Alliance:	Nhlh2tm1Irk page

Germline Transmission:	Earliest citation of germline transmission: J:39356
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region was replaced with a PGK-neo cassette. Transcript was undetected by Northern blot analysis of total RNA isolated from homozygous mutant embryos. (J:39356)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	15 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nhlh2 Mutation:	13 strains or lines available

Original:	J:39356 Good DJ, et al., Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet. 1997 Apr;15(4):397-401
All:	8 reference(s)