Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Arhgdibtm1Len
Name:	Rho, GDP dissociation inhibitor beta; targeted mutation 1, Michael Lenardo
MGI ID:	MGI:2180327
Synonyms:	Ly-GDI-
Gene:	Arhgdib  Location: Chr6:136900653-136918895 bp, - strand  Genetic Position: Chr6, 66.72 cM, cytoband G1
Alliance:	Arhgdibtm1Len page

Germline Transmission:	Earliest citation of germline transmission: J:42604
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin cassette replaced a 1.2-kb region containing exon 3. Neither RNA or protein expression was detected in thymocytes isolated from homozygous mutant animals by Northern and Western blot analysis, respectively. (J:42604)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arhgdib Mutation:	16 strains or lines available

Original:	J:42604 Yin L, et al., Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases. Mol Immunol. 1997 Apr;34(6):481-91
All:	1 reference(s)