Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Daxxtm1Led
Name:	Fas death domain-associated protein; targeted mutation 1, Philip Leder
MGI ID:	MGI:2179457
Gene:	Daxx  Location: Chr17:34128388-34134564 bp, + strand  Genetic Position: Chr17, 17.98 cM
Alliance:	Daxxtm1Led page

Germline Transmission:	Earliest citation of germline transmission: J:56796
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced a 2.5 kb genomic fragment containing exon 1 and part of exon 2. (J:56796)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Daxx Mutation:	33 strains or lines available

Original:	J:56796 Michaelson JS, et al., Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development. Genes Dev. 1999 Aug 1;13(15):1918-23
All:	4 reference(s)