Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fzd5tm1Mmt
Name:	frizzled class receptor 5; targeted mutation 1, Maketo M Taketo
MGI ID:	MGI:2177951
Gene:	Fzd5  Location: Chr1:64769717-64776907 bp, - strand  Genetic Position: Chr1, 32.74 cM
Alliance:	Fzd5tm1Mmt page

Germline Transmission:	Earliest citation of germline transmission: J:52605
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin resistance gene was inserted into the only coding exon of the gene. RT-PCR analysis of RNA derived from homozygous embryos demonstrated that no detectable transcript was produced from this allele. (J:52605)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fzd5 Mutation:	33 strains or lines available

Original:	J:52605 Ishikawa T, et al., Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development. 2001 Jan;128(1):25-33
All:	3 reference(s)