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Anxa6tm1Moss
Targeted Allele Detail
Summary
Symbol: Anxa6tm1Moss
Name: annexin A6; targeted mutation 1, Stephen E Moss
MGI ID: MGI:2159012
Synonyms: annexin 6-, annexin VI-
Gene: Anxa6  Location: Chr11:54869934-54924271 bp, - strand  Genetic Position: Chr11, 32.13 cM
Alliance: Anxa6tm1Moss page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58609
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin selection cassette was inserted into exon 3. Western blot analysis on samples derived from spleen, heart and liver of homozygous mice demonstrated that no detectable protein was produced from this allele. (J:58609)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Anxa6 Mutation:  42 strains or lines available
References
Original:  J:58609 Hawkins TE, et al., Immunological development and cardiovascular function are normal in annexin VI null mutant mice. Mol Cell Biol. 1999 Dec;19(12):8028-32
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory