Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Man2a2tm1Mfu
Name:	mannosidase 2, alpha 2; targeted mutation 1, Michiko N Fukuda
MGI ID:	MGI:2158829
Synonyms:	MX-
Gene:	Man2a2  Location: Chr7:79998845-80021123 bp, - strand  Genetic Position: Chr7, 45.65 cM, cytoband D2
Alliance:	Man2a2tm1Mfu page

Germline Transmission:	Earliest citation of germline transmission: J:73658
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exon 2, which contains the translation initiation site. Western blot analysis using polyclonal antibodies did not detect protein in testes from homozygous mutant mice. (J:73658)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Man2a2 Mutation:	54 strains or lines available

Original:	J:73658 Akama TO, et al., Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science. 2002 Jan 4;295(5552):124-7
All:	4 reference(s)