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Bcl2l1tm1Dlo
Targeted Allele Detail
Summary
Symbol: Bcl2l1tm1Dlo
Name: BCL2-like 1; targeted mutation 1, Dennis Y Loh
MGI ID: MGI:2158303
Synonyms: bcl-x-
Gene: Bcl2l1  Location: Chr2:152622588-152673648 bp, - strand  Genetic Position: Chr2, 75.41 cM, cytoband H1
Alliance: Bcl2l1tm1Dlo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:23793
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic fragment containing the initiation codon was replaced with a neomycin or hygromycin selection cassette. (J:23793)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 61 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl2l1 Mutation:  104 strains or lines available
References
Original:  J:23793 Motoyama N, et al., Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science. 1995 Mar 10;267(5203):1506-10
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory