Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zfp110tm1Mpin
Name:	zinc finger protein 110; targeted mutation 1, Max-Planck-Institute for Neurobiology
MGI ID:	MGI:2156881
Synonyms:	nrif -
Gene:	Zfp110  Location: Chr7:12568688-12584504 bp, + strand  Genetic Position: Chr7, 7.66 cM
Alliance:	Zfp110tm1Mpin page

Germline Transmission:	Earliest citation of germline transmission: J:66924
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The region encoding the p75 binding domain was replaced with a neo cassette. The absence of transcript from the targeted region was confirmed by RT-PCR. (J:66924)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zfp110 Mutation:	32 strains or lines available

Original:	J:66924 Casademunt E, et al., The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. EMBO J. 1999 Nov 1;18(21):6050-61
All:	3 reference(s)