Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cycstm1Wlm
Name:	cytochrome c, somatic; targeted mutation 1, Robert Sanders Williams
MGI ID:	MGI:2154447
Synonyms:	Cyt c-
Gene:	Cycs  Location: Chr6:50539543-50543518 bp, - strand  Genetic Position: Chr6, 24.32 cM
Alliance:	Cycstm1Wlm page

Germline Transmission:	Earliest citation of germline transmission: J:62276
Parent Cell Line:	KG-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced the two protein coding exons. Immunoblot analysis did not detect endogenous protein in cells cultured from E8-E9 embryos of homozygous mutant mice. (J:62276)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cycs Mutation:	9 strains or lines available

Original:	J:62276 Li K, et al., Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis. Cell. 2000 May 12;101(4):389-99
All:	5 reference(s)