Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxd8tm1Jdes
Name:	homeobox D8; targeted mutation 1, Jacqueline Deschamps
MGI ID:	MGI:2151815
Gene:	Hoxd8  Location: Chr2:74534973-74538277 bp, + strand  Genetic Position: Chr2, 44.13 cM, cytoband D
Alliance:	Hoxd8tm1Jdes page

Germline Transmission:	Earliest citation of germline transmission: J:68720
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin cassette was inserted into the sequences in exon 2 which encode the homeodomain. (J:68720)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxd8 Mutation:	11 strains or lines available

Original:	J:68720 van den Akker E, et al., Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes. Development. 2001 May;128(10):1911-21
All:	1 reference(s)