Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gna13tm1Soff
Name:	guanine nucleotide binding protein, alpha 13; targeted mutation 1, Stefan Offermanns
MGI ID:	MGI:2151775
Synonyms:	Galpha13-
Gene:	Gna13  Location: Chr11:109253657-109292195 bp, + strand  Genetic Position: Chr11, 71.88 cM
Alliance:	Gna13tm1Soff page

Germline Transmission:	Earliest citation of germline transmission: J:50566
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic fragment containing the first exon was replaced with a neomycin cassette. RT-PCR analysis did not detect a transcript produced from this allele in homozygous mice. (J:50566)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gna13 Mutation:	12 strains or lines available

Original:	J:50566 Offermanns S, et al., Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science. 1997 Jan 24;275(5299):533-6
All:	9 reference(s)