Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb4tm2Bay
Name:	homeobox B4; targeted mutation 2, Baylor College of Medicine
MGI ID:	MGI:2151429
Synonyms:	hoxb-4s
Gene:	Hoxb4  Location: Chr11:96209093-96212464 bp, + strand  Genetic Position: Chr11, 59.83 cM
Alliance:	Hoxb4tm2Bay page

Germline Transmission:	Earliest citation of germline transmission: J:4612
Parent Cell Line:	AB2.1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Insertion of a 14 bp oligonucleotide that generates a premature stop codon in the second exon, which encodes the third helix of the homeodomain. (J:4612)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb4 Mutation:	18 strains or lines available

Original:	J:4612 Ramirez-Solis R, et al., Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments. Cell. 1993 Apr 23;73(2):279-94
All:	2 reference(s)