Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxa13tm1Ipc
Name:	homeobox A13; targeted mutation 1, I Pierre Chambon
MGI ID:	MGI:2150506
Gene:	Hoxa13  Location: Chr6:52235833-52237865 bp, - strand  Genetic Position: Chr6, 25.41 cM
Alliance:	Hoxa13tm1Ipc page

Germline Transmission:	Earliest citation of germline transmission: J:36214
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin cassette was inserted into sequences encoding the homeobox domain; this mutation generates a disruption of the protein sequence after the 34th amino acid, corresponding to the second alpha helix of the homeodomain. (J:36214)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	45 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa13 Mutation:	29 strains or lines available

Original:	J:36214 Fromental-Ramain C, et al., Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod. Development. 1996 Oct;122(10):2997-3011
All:	11 reference(s)