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Mageb5 Gene Detail
Summary
  • Symbol
    Mageb5
  • Name
    MAGE family member B5
  • Synonyms
    1700056A17Rik, mMage-b5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148169
    NCBI Gene: 74271
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:90823214-90826582 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 40.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148169
 protein coding gene ChrX:90823150-90826624 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035900
 protein coding gene ChrX:87938165-87941640 (+)
A/J MGP_AJ_G0035885
 protein coding gene ChrX:88088611-88092085 (+)
AKR/J MGP_AKRJ_G0035802
 protein coding gene ChrX:90376645-90380119 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034864
 protein coding gene ChrX:73035023-73060792 (+)
CBA/J MGP_CBAJ_G0035552
 protein coding gene ChrX:93354187-93357661 (-)
DBA/2J MGP_DBA2J_G0035707
 protein coding gene ChrX:87324938-87328412 (+)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0035680
 protein coding gene ChrX:97414891-97418365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036424
 protein coding gene ChrX:87632434-87635908 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MAGEB5, MAGE family member B5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEB5, MAGE family member B5
  • Synonyms
    CT3.3, MAGE-B5
  • Links
    NCBI Gene ID: 347541
    neXtProt AC: NX_Q9BZ81
    UniProt: Q9BZ81

  • Chr Location
    Xp21.3; chrX:26216169-26218270 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Mice hemizygous for a deletion of a 30 kb deletion including Mageb5 and a null allele of Mageb5b exhibit normal male fertility despite slightly elongated sperm.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    28
  • cDNA Data
    5
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 74271 NCBI Gene Model | MGI Sequence Detail 3369 C57BL/6J ±  kb
transcript NM_028847 RefSeq | MGI Sequence Detail 1251 Not Specified  
polypeptide NP_083123 RefSeq | MGI Sequence Detail 366 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
    IPR021072 Melanoma associated antigen, N-terminal
Molecular
Reagents
less
  • All nucleic 7
    Genomic 1
    cDNA 5
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1921521
References
more
  • Summaries
    All 29
    Developmental Gene Expression 9
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:334464 Stark-Dykema ER, et al., X-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility. Sci Rep. 2022 May 20;12(1):8554
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory