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Tubg2 Gene Detail
Summary
  • Symbol
    Tubg2
  • Name
    tubulin, gamma 2
  • Synonyms
    Tubgl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144208
    NCBI Gene: 103768
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101046733-101052613 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 64.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    55 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144208
 protein coding gene Chr11:101045945-101052613 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019183
 protein coding gene Chr11:103983198-103989455 (+)
A/J MGP_AJ_G0019151
 protein coding gene Chr11:99618821-99623605 (+)
AKR/J MGP_AKRJ_G0019120
 protein coding gene Chr11:102713004-102721403 (+)
BALB/cJ MGP_BALBcJ_G0019125
 protein coding gene Chr11:100108561-100114828 (+)
C3H/HeJ MGP_C3HHeJ_G0018934
 protein coding gene Chr11:102884920-102889656 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019574
 protein coding gene Chr11:107199056-107210547 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017200
 protein coding gene Chr11:97037149-97042802 (+)
CAST/EiJ MGP_CASTEiJ_G0018488
 protein coding gene Chr11:103873785-103881275 (+)
CBA/J MGP_CBAJ_G0018903
 protein coding gene Chr11:111664192-111670611 (+)
DBA/2J MGP_DBA2J_G0019015
 protein coding gene Chr11:99147817-99154259 (+)
FVB/NJ MGP_FVBNJ_G0019005
 protein coding gene Chr11:98694956-98701110 (+)
LP/J MGP_LPJ_G0019084
 protein coding gene Chr11:104524775-104536417 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019036
 protein coding gene Chr11:111221687-111228307 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019612
 protein coding gene Chr11:103034020-103039563 (+)
PWK/PhJ MGP_PWKPhJ_G0018251
 protein coding gene Chr11:100200367-100204887 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018043
 protein coding gene Chr11:102775166-102783246 (+)
WSB/EiJ MGP_WSBEiJ_G0018537
 protein coding gene Chr11:103034170-103040271 (+)



Homology
more
  • Human Ortholog
    TUBG2, tubulin gamma 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUBG2, tubulin gamma 2
  • Links
    NCBI Gene ID: 27175
    neXtProt AC: NX_Q9NRH3
    UniProt: Q9NRH3

  • Chr Location
    17q21.2; chr17:42659284-42667006 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
  • All Mutations and Alleles
    6
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Tubg2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    16 strains or lines available
Homozygous null mice are viable and fertile with normal weight and no significant histological abnormalities in the brain or other tissues.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1012
  • Tissues
    57
  • cDNA Data
    6
  • Literature Summary
    164
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045007 Ensembl Gene Model | MGI Sequence Detail 5881 C57BL/6J ±  kb
transcript ENSMUST00000043654 Ensembl | MGI Sequence Detail 1754 Not Applicable  
polypeptide ENSMUSP00000045901 Ensembl | MGI Sequence Detail 451 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
Other
Accession IDs
less
MGI:1930396
References
more
  • Summaries
    All 206
    Developmental Gene Expression 164
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:346057 Lu D, et al., ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory