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Nup107 Gene Detail
Summary
  • Symbol
    Nup107
  • Name
    nucleoporin 107
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143854
    NCBI Gene: 103468
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:117586526-117628607 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 66.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    366 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143854
 protein coding gene Chr10:117586526-117628610 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017763
 protein coding gene Chr10:120708971-120755508 (-)
A/J MGP_AJ_G0017738
 protein coding gene Chr10:115975443-116018105 (-)
AKR/J MGP_AKRJ_G0017702
 protein coding gene Chr10:119378171-119418758 (-)
BALB/cJ MGP_BALBcJ_G0017702
 protein coding gene Chr10:116372733-116417016 (-)
C3H/HeJ MGP_C3HHeJ_G0017527
 protein coding gene Chr10:119604560-119651018 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018157
 protein coding gene Chr10:124850829-124897850 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015838
 protein coding gene Chr10:110540657-110584632 (-)
CAST/EiJ MGP_CASTEiJ_G0017087
 protein coding gene Chr10:119906660-119948665 (-)
CBA/J MGP_CBAJ_G0017496
 protein coding gene Chr10:129795419-129844926 (-)
DBA/2J MGP_DBA2J_G0017601
 protein coding gene Chr10:115122387-115165440 (-)
FVB/NJ MGP_FVBNJ_G0017595
 protein coding gene Chr10:114088046-114129796 (-)
LP/J MGP_LPJ_G0017674
 protein coding gene Chr10:121251120-121293455 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017625
 protein coding gene Chr10:132620486-132667245 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018197
 protein coding gene Chr10:119447604-119489110 (-)
PWK/PhJ MGP_PWKPhJ_G0016871
 protein coding gene Chr10:115217393-115267729 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016661
 protein coding gene Chr10:118228184-118271910 (-)
WSB/EiJ MGP_WSBEiJ_G0017148
 protein coding gene Chr10:119636550-119682989 (-)



Homology
more
  • Human Ortholog
    NUP107, nucleoporin 107
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUP107, nucleoporin 107
  • Synonyms
    NPHS11, NUP84, ODG6, ODG6; GAMOS7
  • Links
    NCBI Gene ID: 57122
    neXtProt AC: NX_P57740
    UniProt: P57740

  • Chr Location
    12q15; chr12:68686951-68745809 (+)  GRCh38
Human Diseases
more
  • Diseases
    3 with human NUP107 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a CRISPR-generated allele exhibit reduced female fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    2
  • cDNA Data
    105
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 103468 NCBI Gene Model | MGI Sequence Detail 42082 C57BL/6J ±  kb
    transcript NM_001418950 RefSeq | MGI Sequence Detail 3130 C57BL/6  
    polypeptide Q8BH74 UniProt | EBI | MGI Sequence Detail 926 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 105
      cDNA 105

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143913
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:304858 Olthof AM, et al., Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns. Nucleic Acids Res. 2021 Apr 6;49(6):3524-3545
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory