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Nup205 Gene Detail
Summary
  • Symbol
    Nup205
  • Name
    nucleoporin 205
  • Synonyms
    3830404O05Rik, mKIAA0225
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141625
    NCBI Gene: 70699
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:35154551-35224534 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 15.24 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    388 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141625
 protein coding gene Chr6:35154356-35224534 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030569
 protein coding gene Chr6:33315317-33391366 (+)
A/J MGP_AJ_G0030542
 protein coding gene Chr6:31872149-31942978 (+)
AKR/J MGP_AKRJ_G0030469
 protein coding gene Chr6:32946420-33016253 (+)
BALB/cJ MGP_BALBcJ_G0030552
 protein coding gene Chr6:32053674-32128834 (+)
C3H/HeJ MGP_C3HHeJ_G0030265
 protein coding gene Chr6:32909759-32986535 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031006
 protein coding gene Chr6:34139948-34213923 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028218
 protein coding gene Chr6:29956050-30026785 (+)
CAST/EiJ MGP_CASTEiJ_G0029667
 protein coding gene Chr6:32744541-32828646 (+)
CBA/J MGP_CBAJ_G0030243
 protein coding gene Chr6:35470351-35560129 (+)
DBA/2J MGP_DBA2J_G0030387
 protein coding gene Chr6:31748677-31818643 (+)
FVB/NJ MGP_FVBNJ_G0030341
 protein coding gene Chr6:31545340-31617293 (+)
LP/J MGP_LPJ_G0030474
 protein coding gene Chr6:33418915-33490952 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030377
 protein coding gene Chr6:37771197-37851130 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031036
 protein coding gene Chr6:32828598-32899704 (+)
PWK/PhJ MGP_PWKPhJ_G0029381
 protein coding gene Chr6:31380241-31452204 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029217
 protein coding gene Chr6:32511719-32585387 (+)
WSB/EiJ MGP_WSBEiJ_G0029743
 protein coding gene Chr6:32772894-32846633 (+)



Homology
more
  • Human Ortholog
    NUP205, nucleoporin 205
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUP205, nucleoporin 205
  • Synonyms
    C7orf14, NPHS13
  • Links
    NCBI Gene ID: 23165
    neXtProt AC: NX_Q92621
    UniProt: Q92621

  • Chr Location
    7q33; chr7:135557917-135648757 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NUP205 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70699 NCBI Gene Model | MGI Sequence Detail 69984 C57BL/6J ±  kb
    transcript NM_027513 RefSeq | MGI Sequence Detail 6244 C57BL/6  
    polypeptide NP_081789 RefSeq | MGI Sequence Detail 2008 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      11 Sequences
    • InterPro Domains
      IPR021827 Nucleoporin Nup186/Nup192/Nup205
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1917949
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:263646 Horiuchi K, et al., Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. Cell Rep. 2018 Apr 3;23(1):143-155
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory