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Phf24 Gene Detail
Summary
  • Symbol
    Phf24
  • Name
    PHD finger protein 24
  • Synonyms
    GINIP, mKIAA1045, N28178
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140712
    NCBI Gene: 230085
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:42916660-42944752 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 22.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140712
protein coding gene Chr4:42872619-42944752 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028193
protein coding gene Chr4:40989697-41017579 (+)
A/J MGP_AJ_G0028149
protein coding gene Chr4:39554932-39583121 (+)
AKR/J MGP_AKRJ_G0028101
protein coding gene Chr4:40451725-40479762 (+)
BALB/cJ MGP_BALBcJ_G0028169
protein coding gene Chr4:39641629-39669641 (+)
C3H/HeJ MGP_C3HHeJ_G0027891
protein coding gene Chr4:41080679-41108543 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028610
protein coding gene Chr4:42518935-42550754 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025922
protein coding gene Chr4:37022779-37045168 (+)
CAST/EiJ MGP_CASTEiJ_G0027331
protein coding gene Chr4:40551554-40579447 (+)
CBA/J MGP_CBAJ_G0027857
protein coding gene Chr4:43856839-43885877 (+)
DBA/2J MGP_DBA2J_G0028006
protein coding gene Chr4:39465021-39492875 (+)
FVB/NJ MGP_FVBNJ_G0027973
protein coding gene Chr4:38690842-38719423 (+)
LP/J MGP_LPJ_G0028105
protein coding gene Chr4:41061704-41090531 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027997
protein coding gene Chr4:47113667-47144061 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028646
protein coding gene Chr4:40650285-40678155 (+)
PWK/PhJ MGP_PWKPhJ_G0027057
protein coding gene Chr4:39502826-39531253 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026883
protein coding gene Chr4:40203623-40231332 (+)
WSB/EiJ MGP_WSBEiJ_G0027411
protein coding gene Chr4:40554279-40584818 (+)



Homology
more
  • Human Ortholog
    PHF24, PHD finger protein 24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF24, PHD finger protein 24
  • Synonyms
    GINIP
  • Links
    NCBI Gene ID: 23349
    neXtProt AC: NX_Q9UPV7
    UniProt: Q9UPV7

  • Chr Location
    9p13.3; chr9:34665607-34982544 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from multigenic genotypes
    10 phenotype references
Mice homozygous for a knock-out allele develop a selective and prolonged mechanical hypersensitivity in models of inflammation and neuropathy and show impaired baclofen-mediated analgesia following nerve injury.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036062 Ensembl Gene Model | MGI Sequence Detail 28093 C57BL/6J ±  kb
transcript ENSMUST00000107975 Ensembl | MGI Sequence Detail 6494 Not Applicable  
polypeptide ENSMUSP00000103609 Ensembl | MGI Sequence Detail 400 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    cDNA 41
    Primer pair 2

    Microarray probesets 6
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
  • Latest
    J:338221 Park JC, et al., Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits. Mol Cell. 2023 Jul 20;83(14):2540-2558.e12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory