Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Apcstm1Mpe
Name:	amyloid P component, serum; targeted mutation 1, Mark B Pepys
MGI ID:	MGI:2138028
Synonyms:	SAP-
Gene:	Apcs  Location: Chr1:172721528-172722516 bp, - strand  Genetic Position: Chr1, 80.33 cM
Alliance:	Apcstm1Mpe page

Germline Transmission:	Earliest citation of germline transmission: J:42137
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin cassette replaced the entire coding region of the gene. (J:42137)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apcs Mutation:	21 strains or lines available

Original:	J:42137 Botto M, et al., Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene. Nat Med. 1997 Aug;3(8):855-9
All:	10 reference(s)