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Pabpc5 Gene Detail
Summary
  • Symbol
    Pabpc5
  • Name
    poly(A) binding protein, cytoplasmic 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136401
    NCBI Gene: 93728
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:118836893-118839862 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 49.58 cM, cytoband D
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136401
 protein coding gene ChrX:118836893-118839862 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036044
 protein coding gene ChrX:116789949-116793452 (+)
A/J MGP_AJ_G0036025
 protein coding gene ChrX:116411552-116414529 (+)
AKR/J MGP_AKRJ_G0035943
 protein coding gene ChrX:120201761-120204730 (+)
BALB/cJ MGP_BALBcJ_G0036017
 protein coding gene ChrX:114877052-114880096 (+)
C3H/HeJ MGP_C3HHeJ_G0035723
 protein coding gene ChrX:117042777-117046516 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036541
 protein coding gene ChrX:120287900-120291032 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033367
 protein coding gene ChrX:112601178-112604179 (+)
CAST/EiJ MGP_CASTEiJ_G0035010
 protein coding gene ChrX:100814066-100817036 (+)
CBA/J MGP_CBAJ_G0035698
 protein coding gene ChrX:124054484-124058782 (+)
DBA/2J MGP_DBA2J_G0035849
 protein coding gene ChrX:115754877-115757812 (+)
FVB/NJ MGP_FVBNJ_G0035793
 protein coding gene ChrX:115074836-115077806 (+)
LP/J MGP_LPJ_G0035943
 protein coding gene ChrX:117666540-117669509 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035822
 protein coding gene ChrX:130132625-130135594 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036568
 protein coding gene ChrX:116289052-116291813 (+)
PWK/PhJ MGP_PWKPhJ_G0034702
 protein coding gene ChrX:98118630-98121525 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034533
 protein coding gene ChrX:101566970-101569953 (+)
WSB/EiJ MGP_WSBEiJ_G0035146
 protein coding gene ChrX:114941771-114945836 (+)



Homology
more
  • Human Ortholog
    PABPC5, poly(A) binding protein cytoplasmic 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PABPC5, poly(A) binding protein cytoplasmic 5
  • Synonyms
    PABP5
  • Links
    NCBI Gene ID: 140886
    neXtProt AC: NX_Q96DU9
    UniProt: Q96DU9

  • Chr Location
    Xq21.31; chrX:91434595-91438584 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    22
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 93728 NCBI Gene Model | MGI Sequence Detail 2970 C57BL/6J ±  kb
    transcript NM_053114 RefSeq | MGI Sequence Detail 2434 C57BL/6  
    polypeptide NP_444344 RefSeq | MGI Sequence Detail 381 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR034364 PABP, RNA recognition motif 1
      IPR045305 PABP, RNA recognition motif 2
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
      IPR003954 RNA recognition motif domain, eukaryote
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 6
      Primer pair 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 18
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 2
    • Earliest
      J:69922 Blanco P, et al., A Novel Poly(A)-Binding Protein Gene (PABPC5) Maps to an X-Specific Subinterval in the Xq21.3/Yp11.2 Homology Block of the Human Sex Chromosomes. Genomics. 2001 May 15;74(1):1-11
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    04/16/2024
    MGI 6.23     		The Jackson Laboratory