Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Atmtm1Pmc
Name:	ataxia telangiectasia mutated; targeted mutation 1, Peter J McKinnon
MGI ID:	MGI:1933746
Synonyms:	Atm-
Gene:	Atm  Location: Chr9:53350449-53448040 bp, - strand  Genetic Position: Chr9, 29.12 cM, cytoband C-D
Alliance:	Atmtm1Pmc page

Germline Transmission:	Earliest citation of germline transmission: J:47752
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin gene interrupts exon 57 and replaces exon 58. This region corresponds to a region deleted in some human AT deficiency cases. (J:47752) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atm Mutation:	169 strains or lines available

Original:	J:47752 Herzog KH, et al., Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science. 1998 May 15;280(5366):1089-91
All:	37 reference(s)