Lfngtm1Rjo
Targeted Allele Detail
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Symbol: |
Lfngtm1Rjo |
Name: |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1, Randy L Johnson |
MGI ID: |
MGI:1933737 |
Synonyms: |
Lfng- |
Gene: |
Lfng Location: Chr5:140593096-140601300 bp, + strand Genetic Position: Chr5, 79.15 cM
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Alliance: |
Lfngtm1Rjo page
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Irregular sacral segmentation in Hes7tm1Kag/Hes7tm1Kag mice
Show the 4 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:48859
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Parent Cell Line: |
AB1 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1+
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neomycin resistance cassette replaced exon 1 of the Lnfg gene, including the translational start site, the signal sequence, and a putative processing site. The authors predict the mutant allele would be a null mutation, and report that Lnfg mRNA is not detected in homozygous mutant embryos.
(J:48859)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lfng Mutation: |
32 strains or lines available
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Original: |
J:48859 Evrard YA, et al., lunatic fringe is an essential mediator of somite segmentation and patterning. Nature. 1998 Jul 23;394(6691):377-81 |
All: |
25 reference(s) |
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