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Maged2 Gene Detail
Summary
  • Symbol
    Maged2
  • Name
    MAGE family member D2
  • Synonyms
    4833439A22Rik, Mage-d2, ORF1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933391
    NCBI Gene: 80884
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:149589417-149597358 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 68.46 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933391
protein coding gene ChrX:149589366-149597358 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036172
protein coding gene ChrX:148527658-148535630 (-)
A/J MGP_AJ_G0036148
protein coding gene ChrX:147727141-147735107 (-)
AKR/J MGP_AKRJ_G0036074
protein coding gene ChrX:152501068-152509002 (-)
BALB/cJ MGP_BALBcJ_G0036139
protein coding gene ChrX:145941272-145949230 (-)
C3H/HeJ MGP_C3HHeJ_G0035847
protein coding gene ChrX:148718458-148726433 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036664
protein coding gene ChrX:152713476-152721611 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033488
protein coding gene ChrX:139532295-139540215 (-)
CAST/EiJ MGP_CASTEiJ_G0035138
protein coding gene ChrX:128174578-128182482 (-)
CBA/J MGP_CBAJ_G0035824
protein coding gene ChrX:157244050-157252023 (-)
DBA/2J MGP_DBA2J_G0035982
protein coding gene ChrX:146823627-146833272 (-)
FVB/NJ MGP_FVBNJ_G0035916
protein coding gene ChrX:145970701-145978657 (-)
LP/J MGP_LPJ_G0036073
protein coding gene ChrX:149593375-149601345 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035952
protein coding gene ChrX:165341166-165349123 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036699
protein coding gene ChrX:148029855-148037829 (-)
PWK/PhJ MGP_PWKPhJ_G0034832
protein coding gene ChrX:125152107-125160274 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034658
protein coding gene ChrX:128630072-128639769 (-)
WSB/EiJ MGP_WSBEiJ_G0035273
protein coding gene ChrX:146128250-146136231 (-)



Homology
more
  • Human Ortholog
    MAGED2, MAGE family member D2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGED2, MAGE family member D2
  • Synonyms
    11B6, BARTS5, BCG1, BCG-1, HCA10, MAGE-D2
  • Links
    NCBI Gene ID: 10916
    neXtProt AC: NX_Q9UNF1
    UniProt: Q9UNF1

  • Chr Location
    Xp11.21; chrX:54807599-54816015 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human MAGED2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 80884 NCBI Gene Model | MGI Sequence Detail 7942 C57BL/6J ±  kb
transcript NM_001358568 RefSeq | MGI Sequence Detail 2257 C57BL/6  
polypeptide NP_001345496 RefSeq | MGI Sequence Detail 616 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922040
References
more
  • Summaries
    All 42
    Developmental Gene Expression 13
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:310310 Gordeeva O, et al., Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells. Oncotarget. 2019 May 14;10(35):3248-3266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory