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Trim23 Gene Detail
Summary
  • Symbol
    Trim23
  • Name
    tripartite motif-containing 23
  • Synonyms
    6330516O20Rik, Arfd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933161
    NCBI Gene: 81003
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:104315305-104339880 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 56.35 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    213 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933161
 protein coding gene Chr13:104315187-104339983 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020905
 protein coding gene Chr13:106269452-106293975 (+)
A/J MGP_AJ_G0020856
 protein coding gene Chr13:102133951-102158517 (+)
AKR/J MGP_AKRJ_G0020831
 protein coding gene Chr13:105244264-105268843 (+)
BALB/cJ MGP_BALBcJ_G0020856
 protein coding gene Chr13:102842901-102867450 (+)
C3H/HeJ MGP_C3HHeJ_G0020645
 protein coding gene Chr13:104980049-105004365 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021290
 protein coding gene Chr13:109464717-109489318 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018860
 protein coding gene Chr13:97751472-97777827 (+)
CAST/EiJ MGP_CASTEiJ_G0020165
 protein coding gene Chr13:104445450-104473261 (+)
CBA/J MGP_CBAJ_G0020607
 protein coding gene Chr13:113714111-113740704 (+)
DBA/2J MGP_DBA2J_G0020731
 protein coding gene Chr13:101899492-101924100 (+)
FVB/NJ MGP_FVBNJ_G0020713
 protein coding gene Chr13:100597444-100621867 (+)
LP/J MGP_LPJ_G0020805
 protein coding gene Chr13:106294820-106319694 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020741
 protein coding gene Chr13:113879226-113927201 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021329
 protein coding gene Chr13:104718354-104742642 (+)
PWK/PhJ MGP_PWKPhJ_G0019918
 protein coding gene Chr13:100634009-100658943 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019740
 protein coding gene Chr13:100914754-100942104 (+)
WSB/EiJ MGP_WSBEiJ_G0020222
 protein coding gene Chr13:105185928-105211249 (+)



Homology
more
  • Human Ortholog
    TRIM23, tripartite motif containing 23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM23, tripartite motif containing 23
  • Synonyms
    ARD1, ARFD1, RNF46
  • Links
    NCBI Gene ID: 373
    neXtProt AC: NX_P36406
    UniProt: P36406

  • Chr Location
    5q12.3; chr5:65589690-65625975 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Mice homozygous for a gene trapped allele exhibit mild myopathy with sarcotubular myopathy, decreased fertility, and decreased axon diameter.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    15
  • cDNA Data
    14
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021712 Ensembl Gene Model | MGI Sequence Detail 24576 C57BL/6J ±  kb
transcript ENSMUST00000022225 Ensembl | MGI Sequence Detail 3416 Not Applicable  
polypeptide ENSMUSP00000022225 Ensembl | MGI Sequence Detail 574 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 7
Other
Accession IDs
less
MGI:1923425, MGI:2145241
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:306292 Cao X, et al., Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels. J Biol Chem. 2021 May 3;:100738
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory