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Acox3 Gene Detail
Summary
  • Symbol
    Acox3
  • Name
    acyl-Coenzyme A oxidase 3, pristanoyl
  • Synonyms
    EST-s59, PCOX, pristanoyl-CoA oxidase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933156
    NCBI Gene: 80911
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:35740293-35772397 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 18.32 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933156
 protein coding gene Chr5:35740293-35772696 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029481
 protein coding gene Chr5:33870799-33908793 (+)
A/J MGP_AJ_G0029448
 protein coding gene Chr5:32763847-32796110 (+)
AKR/J MGP_AKRJ_G0029397
 protein coding gene Chr5:34021913-34058357 (+)
BALB/cJ MGP_BALBcJ_G0029458
 protein coding gene Chr5:33283497-33316273 (+)
C3H/HeJ MGP_C3HHeJ_G0029180
 protein coding gene Chr5:34039058-34072699 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029912
 protein coding gene Chr5:35784121-35817756 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027149
 protein coding gene Chr5:30527316-30560986 (+)
CAST/EiJ MGP_CASTEiJ_G0028589
 protein coding gene Chr5:33134532-33168298 (+)
CBA/J MGP_CBAJ_G0029148
 protein coding gene Chr5:36624115-36663232 (+)
DBA/2J MGP_DBA2J_G0029296
 protein coding gene Chr5:32914329-32947046 (+)
FVB/NJ MGP_FVBNJ_G0029255
 protein coding gene Chr5:32380489-32413616 (+)
LP/J MGP_LPJ_G0029381
 protein coding gene Chr5:34304919-34340667 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029285
 protein coding gene Chr5:37425784-37458042 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029945
 protein coding gene Chr5:33525551-33557702 (+)
PWK/PhJ MGP_PWKPhJ_G0028314
 protein coding gene Chr5:32077732-32114104 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028145
 protein coding gene Chr5:32979784-33029145 (+)
WSB/EiJ MGP_WSBEiJ_G0028670
 protein coding gene Chr5:33587882-33620026 (+)



Homology
more
  • Human Ortholog
    ACOX3, acyl-CoA oxidase 3, pristanoyl
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACOX3, acyl-CoA oxidase 3, pristanoyl
  • Links
    NCBI Gene ID: 8310
    neXtProt AC: NX_O15254
    UniProt: O15254

  • Chr Location
    4p16.1; chr4:8355305-8440723 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    837
  • Tissues
    126
  • cDNA Data
    32
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 80911 NCBI Gene Model | MGI Sequence Detail 32105 C57BL/6J ±  kb
    transcript NM_001357018 RefSeq | MGI Sequence Detail 4136 C57BL/6  
    polypeptide Q9EPL9 UniProt | EBI | MGI Sequence Detail 700 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000003644 peroxisomal acyl-coenzyme A oxidase 3
      (term hierarchy)
    • EC
      1.3.3.6
    • InterPro Domains
      IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
      IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal
      IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
      IPR012258 Acyl-CoA oxidase
      IPR002655 Acyl-CoA oxidase, C-terminal
      IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain
      IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
      IPR034171 Peroxisomal acyl-coenzyme A oxidase
    Molecular
    Reagents
    less
    • All nucleic 35
      cDNA 33
      Primer pair 1
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2183033
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 7
      Phenotypes 29
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory