Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgf4tm1.3Mrt
Name:	fibroblast growth factor 4; targeted mutation 1.3, Gail R Martin
MGI ID:	MGI:1931063
Synonyms:	Fgf4delta2,3
Gene:	Fgf4  Location: Chr7:144415123-144418982 bp, + strand  Genetic Position: Chr7, 88.88 cM
Alliance:	Fgf4tm1.3Mrt page

Germline Transmission:	Earliest citation of germline transmission: J:61886
Parent Cell Line:	CGR8 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: This allele is a derivative of Fgf4tm1.2Mrt where the exons 2 and 3 were removed by Cre-mediated recombination by crossing mice carrying the Fgf4tm1.2Mrt allele with mice expressing Cre recombinase under the control of a beta-actin promoter (TgNACTB-Cre)2Mrt). (J:61886)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

63 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf4 Mutation:	29 strains or lines available

Original:	J:61886 Sun X, et al., Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet. 2000 May;25(1):83-6
All:	6 reference(s)