Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hgftm1Kita
Name:	hepatocyte growth factor; targeted mutation 1, Naomi Kitamura
MGI ID:	MGI:1929776
Synonyms:	hgf-, HGF/SF-
Gene:	Hgf  Location: Chr5:16758493-16825150 bp, + strand  Genetic Position: Chr5, 7.07 cM, cytoband A2-A3
Alliance:	Hgftm1Kita page

Germline Transmission:	Earliest citation of germline transmission: J:23171
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Disruption of the Hgf gene by deletion of part of exon 5, encoding the first kringle domain, and replacement of these sequences with a PGK- neomycin cassette. (J:23171) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hgf Mutation:	55 strains or lines available

Original:	J:23171 Uehara Y, et al., Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature. 1995 Feb 23;373(6516):702-5
All:	3 reference(s)