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Xpo7 Gene Detail
Summary
  • Symbol
    Xpo7
  • Name
    exportin 7
  • Synonyms
    4930506C02Rik, Ranbp16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929705
    NCBI Gene: 65246
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:70899566-71004075 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 36.44 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    401 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929705
 protein coding gene Chr14:70891686-71004075 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021549
 protein coding gene Chr14:65320122-65430772 (-)
A/J MGP_AJ_G0021508
 protein coding gene Chr14:63923159-64027773 (-)
AKR/J MGP_AKRJ_G0021484
 protein coding gene Chr14:65840730-65952466 (-)
BALB/cJ MGP_BALBcJ_G0021514
 protein coding gene Chr14:63686740-63793248 (-)
C3H/HeJ MGP_C3HHeJ_G0021291
 protein coding gene Chr14:65558250-65667889 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021953
 protein coding gene Chr14:68227730-68338994 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019493
 protein coding gene Chr14:61762079-61865334 (-)
CAST/EiJ MGP_CASTEiJ_G0020808
 protein coding gene Chr14:62153278-62262353 (-)
CBA/J MGP_CBAJ_G0021258
 protein coding gene Chr14:70382217-70496240 (-)
DBA/2J MGP_DBA2J_G0021381
 protein coding gene Chr14:63310523-63417711 (-)
FVB/NJ MGP_FVBNJ_G0021360
 protein coding gene Chr14:62738711-62846355 (-)
LP/J MGP_LPJ_G0021452
 protein coding gene Chr14:66564718-66669433 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021389
 protein coding gene Chr14:69260089-69379768 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021977
 protein coding gene Chr14:65103052-65213402 (-)
PWK/PhJ MGP_PWKPhJ_G0020552
 protein coding gene Chr14:60078727-60185728 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020385
 protein coding gene Chr14:61035124-61139362 (-)
WSB/EiJ MGP_WSBEiJ_G0020861
 protein coding gene Chr14:65414272-65525794 (-)



Homology
more
  • Human Ortholog
    XPO7, exportin 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    XPO7, exportin 7
  • Synonyms
    EXP7, RANBP16
  • Links
    NCBI Gene ID: 23039
    neXtProt AC: NX_Q9UIA9
    UniProt: Q9UIA9

  • Chr Location
    8p21.3; chr8:21919662-22006585 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 4 alleles in 4 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit impaired stress erythropoiesis, mild anemia, and partial lethality during organogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    7
  • cDNA Data
    24
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 65246 NCBI Gene Model | MGI Sequence Detail 104510 C57BL/6J ±  kb
    transcript NM_023045 RefSeq | MGI Sequence Detail 7245 C57BL/6  
    polypeptide Q9EPK7 UniProt | EBI | MGI Sequence Detail 1087 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 26
      Primer pair 3

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1922351, MGI:2145856
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:65836 Koch P, et al., Identification of a novel putative ran-binding protein and its close homologue. Biochem Biophys Res Commun. 2000 Nov 11;278(1):241-9
    • Latest
      J:331429 Modepalli S, et al., An In Vivo Model for Elucidating the Role of an Erythroid-Specific Isoform of Nuclear Export Protein Exportin 7 (Xpo7) in Murine Erythropoiesis. Exp Hematol. 2022 Aug 13;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory