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Bean1 Gene Detail
Summary
  • Symbol
    Bean1
  • Name
    brain expressed, associated with Nedd4, 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929597
    NCBI Gene: 65115
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:104897110-104945730 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929597
 protein coding gene Chr8:104897074-104945754 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034001
 protein coding gene Chr8:106278634-106332753 (+)
A/J MGP_AJ_G0033982
 protein coding gene Chr8:102059518-102108037 (+)
AKR/J MGP_AKRJ_G0033909
 protein coding gene Chr8:105017283-105067791 (+)
BALB/cJ MGP_BALBcJ_G0033975
 protein coding gene Chr8:102285628-102338051 (+)
C3H/HeJ MGP_C3HHeJ_G0033687
 protein coding gene Chr8:105711972-105765192 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034496
 protein coding gene Chr8:110183782-110238339 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031439
 protein coding gene Chr8:95369640-95417194 (+)
CAST/EiJ MGP_CASTEiJ_G0033017
 protein coding gene Chr8:105286588-105342787 (+)
CBA/J MGP_CBAJ_G0033661
 protein coding gene Chr8:113817411-113866009 (+)
DBA/2J MGP_DBA2J_G0033815
 protein coding gene Chr8:101424526-101473375 (+)
FVB/NJ MGP_FVBNJ_G0033762
 protein coding gene Chr8:100361564-100411253 (+)
LP/J MGP_LPJ_G0033906
 protein coding gene Chr8:106457403-106513265 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033804
 protein coding gene Chr8:117003437-117058144 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034514
 protein coding gene Chr8:104984620-105033689 (+)
PWK/PhJ MGP_PWKPhJ_G0032718
 protein coding gene Chr8:100833060-100883138 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032556
 protein coding gene Chr8:103809518-103857563 (+)
WSB/EiJ MGP_WSBEiJ_G0033130
 protein coding gene Chr8:105652290-105702453 (+)



Homology
more
  • Human Ortholog
    BEAN1, brain expressed associated with NEDD4 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BEAN1, brain expressed associated with NEDD4 1
  • Synonyms
    BEAN, SCA31
  • Links
    NCBI Gene ID: 146227
    neXtProt AC: NX_Q3B7T3
    UniProt: Q3B7T3

  • Chr Location
    16q21; chr16:66427295-66495288 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human BEAN1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null targeted allele are viable and fertile and exhibit no apparent abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 65115 NCBI Gene Model | MGI Sequence Detail 48621 C57BL/6J ±  kb
transcript NM_001141922 RefSeq | MGI Sequence Detail 3315 C57BL/6  
polypeptide Q9EQG5 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65663 Jolliffe CN, et al., Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase nedd4. Biochem J. 2000 Nov 1;351 Pt 3:557-65
  • Latest
    J:314906 Khang R, et al., Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Sci Rep. 2021 Nov 23;11(1):22745
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory