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Grin2ctm1Nts
Targeted Allele Detail
Summary
Symbol: Grin2ctm1Nts
Name: glutamate receptor, ionotropic, NMDA2C (epsilon 3); targeted mutation 1, N Traverse Slater
MGI ID: MGI:1928301
Synonyms: NR2C -
Gene: Grin2c  Location: Chr11:115139995-115158069 bp, - strand  Genetic Position: Chr11, 80.8 cM
Alliance: Grin2ctm1Nts page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:34597
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of the exon encoding the M2 transmembrane segment with a neomycin cassette. (J:34597)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grin2c Mutation:  56 strains or lines available
References
Original:  J:34597 Ebralidze AK, et al., Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene. J Neurosci. 1996 Aug 15;16(16):5014-25
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory