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Fgf6tm1Thbr
Targeted Allele Detail
Summary
Symbol: Fgf6tm1Thbr
Name: fibroblast growth factor 6; targeted mutation 1, Thomas Braun
MGI ID: MGI:1927559
Synonyms: FGF-6-, FGF6-
Gene: Fgf6  Location: Chr6:126992505-127001681 bp, + strand  Genetic Position: Chr6, 61.92 cM, cytoband F3-G1
Alliance: Fgf6tm1Thbr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42574
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced 3.8 kb of sequence. Most of exon 1, intron 1, exon 2 and part of exon 2 were deleted. (J:42574)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf6 Mutation:  7 strains or lines available
References
Original:  J:42574 Floss T, et al., A role for FGF-6 in skeletal muscle regeneration. Genes Dev. 1997 Aug 15;11(16):2040-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory