About   Help   FAQ
Ring1tm1Mvi
Targeted Allele Detail
Summary
Symbol: Ring1tm1Mvi
Name: ring finger protein 1; targeted mutation 1, Miguel Vidal
MGI ID: MGI:1926913
Synonyms: Ring1A-
Gene: Ring1  Location: Chr17:34239766-34243654 bp, - strand  Genetic Position: Chr17, 17.98 cM
Alliance: Ring1tm1Mvi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65300
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsDeletion of the first six exons, including the sequences encoding the translation initiation start site, the RING finger domain, the homology domain 2 and part of the homology domain 3. These sequences were replaced with an HPRT minigene. (J:65300)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ring1 Mutation:  17 strains or lines available
References
Original:  J:65300 del Mar Lorente M, et al., Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice. Development. 2000 Dec;127(23):5093-100
All:  39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory